Therapeutic plasma exchange (TPE) is an extracorporeal procedure of blood purification that is applied to treat patients with a range of conditions. TPE is a relatively common treatment modality nowadays. It shows positive clinical outcomes in the management of Guillain-Barré syndrome, thrombotic thrombocytopenic purpura (TTP), myasthenia gravis, and Goodpasture syndrome.

The Therapeutic Plasma Exchange market is set to show a growth rate of about 7.98% during the forecast period (2025-2033F). The therapeutic plasma exchange (TPE) market is fueled by the increase in the incidence of autoimmune and neurological diseases like myasthenia gravis, Guillain-Barré syndrome, and multiple sclerosis. The market is also boosted by a growing awareness of advanced treatment products, increasing demand for plasma-derived therapies, and the rising adoption in critical care. Adoption is also supported by technological innovations in apheresis devices, making it easy to use in different healthcare settings.

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List of Top Companies Operating in Therapeutic Plasma Exchange Worldwide:

The global therapeutic plasma exchange market has several major players, including Nikkiso Co., Ltd., B. Braun SE, Fresenius Medical Care, Asahi Kasei Corporation, and Terumo Corporation. More information about these companies has been provided below:

1.      Nikkiso Co., Ltd.

Nikkiso Co., Ltd. engages in industrial, aerospace, and medical businesses worldwide. The company offers hemodialysis systems, blood tubing lines, dialysis/filters, artificial pancreas, and acute blood purification; and deep UV-LEDs for water purification, air purification, analysis, and medical applications. The company was formerly known as Nippon Kikai Keiso Kaisha Ltd. and changed its name to Nikkiso Co., Ltd. in November 1968. The company was incorporated in 1950 and is headquartered in Tokyo, Japan.

2.      Fresenius Medical Care

Fresenius Medical Care AG provides dialysis and related services for individuals with renal diseases in Germany, the United States, and internationally. The company offers dialysis treatment and related laboratory and diagnostic services through a network of outpatient dialysis clinics. It also develops, manufactures, and distributes various healthcare products, including polysulfone dialyzers, hemodialysis machines, peritoneal dialysis cyclers, peritoneal dialysis solutions, hemodialysis concentrates, solutions and granulates, bloodlines, and renal pharmaceuticals systems. The company sells its products to dialysis clinics, hospitals, and specialized treatment clinics, as well as through local sales forces, independent distributors, dealers, and sales agents.

3.      B. Braun SE

B. Braun SE is a healthcare equipment company. It was founded in 1838 and is based in Melsungen, Germany. B. Braun SE is a leading global healthcare company, specializing in medical devices, pharmaceutical products, and healthcare services. In the therapeutic plasma exchange (TPE) space, B. Braun offers advanced apheresis systems and solutions, supporting efficient and safe plasma removal and replacement for various autoimmune and neurological disorders.

4.      Asahi Kasei Corporation

The Asahi Kasei Group contributes to life and living for people around the world. Since its foundation in 1922 with the ammonia and cellulose fiber business, Asahi Kasei has consistently grown through the proactive transformation of its business portfolio to meet the evolving needs of every age. With more than 48,000 employees around the world, the company contributes to a sustainable society by providing solutions to the world’s challenges through its three business sectors of material, homes, and healthcare. The healthcare segment provides pharmaceuticals and diagnostic reagents, dialyzers, therapeutic apheresis, virus removal filters, defibrillators, AEDs, automated CPRs, fluid resuscitation pumps, and wearable defibrillators.

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5.      Terumo Corporation

Terumo Corporation engages in the manufacture and sale of medical products and equipment in Japan, Europe, China, the United States, Asia, and internationally. It operates through three segments: Cardiac and Vascular Company, Medical Care Solutions Company, and Blood and Cell Technologies Company. The Blood and Cell Technologies Company segment offers blood bags, component collection systems, automated blood processing systems, pathogen reduction systems, centrifugal apheresis systems, cell expansion systems, and others. The company was formerly known as Sekisen Ken-onki Corporation and changed its name to Terumo Corporation in October 1974. Terumo Corporation was incorporated in 1921 and is headquartered in Tokyo, Japan.

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