Understanding the 24-Hour Urine Ketosteroids Test: Purpose and Procedure
What Is the 24-Hour Urine Ketosteroids Test?
Ketosteroids are substances formed when the body breaks down steroid hormones produced by the adrenal glands and gonads (ovaries and testes). By measuring their combined levels in urine collected over 24 hours, healthcare providers can evaluate the function of the adrenal cortex and detect disorders like Cushing’s syndrome, congenital adrenal hyperplasia, or other hormonal imbalances.
Why Is This Test Done?
To diagnose conditions involving excess or deficient steroid hormone production
To monitor treatment of adrenal gland disorders
To evaluate symptoms such as abnormal growth, virilization, or hormonal dysfunction
To assist in diagnosing certain tumors of the adrenal or gonadal glands
How Is the Test Conducted?
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Patients collect all their urine over a 24-hour period in a provided container, starting after the first morning void.
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It is vital to collect every urine sample during this period and store the container as instructed (often refrigerated).
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No special dietary restrictions are typically required, but patients should inform their doctor about medications that could influence results.
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The total urine volume is measured, and ketosteroids are quantified using laboratory techniques like chromatography.
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What to Expect?
The test is non-invasive and requires patient compliance for accurate sampling. The results inform doctors about hormone metabolism and help tailor treatment plans for endocrine disorders.
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